Our study also found elevated muscle enzyme values [ALT (P < .001), AST (P < .001), CK (P < .001), CK-MB (P < .001), CTNI (P < .001), and LDH (P < .001)] in patients with anti-Mi antibody positivity which were significantly higher than the other subtypes, and the occurrence of symptoms of muscle involvement such as myalgias and myalgia was also high, second only to anti-NXP2 antibody. This evidence concerns the gene MITF and Myalgia.