Song et al identified that the knock-down of lncRNA CBR3-AS1 significantly suppressed colorectal cancer cell proliferation, migration, and invasion, while high lncRNA BLACAT1 expression served as a poor prognostic factor for colorectal cancer cell patients.[11] Zhang et al found that lncRNA CBR3-AS1 was highly expressed in osteosarcoma tissues and cell lines and correlated with Enneking stage, distant metastasis, and histological grading. This evidence concerns the gene CBR3 and osteosarcoma.