Activation of the cGAS-STING axis may increase the risk of endothelial cell death by inducing macrophages in areas of endothelial inflammation that are affected by multiple cytokines alongside interleukin-6 (which is a neutrophil chemoattractant).[76,77] Furthermore, the detection of cGAS-STING activity in lung samples from severe COVID-19 patients offers a potential explanation for the observed vascular injury and coagulopathy in those severe patients.[78] Studies indicate a decrease in blood Myristate concentration following pathogen invasion. The gene discussed is CGAS; the disease is COVID-19.