PANX3 and papilloma: Survival curves for time to papilloma onset showed weak evidence for differences between genotypes (Fig. 6D, P = 0.176); however, the average response latency to first papilloma formation (for mice that developed papillomas) was similar, with WT mice developing papillomas after 25.7 weeks and Panx3 KO mice developing papillomas after 25.2 weeks.