The correlation between baseline T-tau, p-181 tau and hippocampal atrophy showed a significant correlation between tau and hippocampal atrophy in A.H.T.-users (p-181 tau: P=0.007; T-tau: P=0.052) but not in non-users (p-181 tau: P=0.382; T-tau: P=0.677). This evidence concerns the gene MAPT and hippocampal atrophy.