Parasite infections can elicit a type 1 immune response characterized by the elevation of T helper 1 (Th1) cytokines such as interferon-γ, or a type 2 immune response featured by the production of Th2 cytokines such as interleukin 4 (IL-4), IL-5, and IL-13 (Engwerda et al., 2014; Zaiss et al., 2024). The gene discussed is IL4; the disease is parasitic infectious disease.