Autologous hematopoietic stem cell transplantation (ASCT) for MM may be associated with infection and engraftment syndrome (ES), both of which are associated with fever and elevated CRP, but only patients with bacteremia had elevated PCT levels, whereas all other patients had PCT levels below 2 ng/mL, with a PCT threshold of <2 ng/mL, which can be used to identify patients with ES-associated noninfectious fever after ASCT (Knoll et al., 2019). The gene discussed is CALCA; the disease is bacterial infectious disease with sepsis.