CXCL8 and infection: In the study of infection indicators in neonatal sepsis, the investigators collected blood samples at three time points (0 h, 12-24 h, and 48-72 h) and found that IL-6 and SAA were elevated in the confirmed sepsis group (CSG), and the suspected sepsis group (SSG) compared to the control group at 0 h, and SAA was elevated at 12-24 h, IL-8 and SAA were elevated at 48-72 h (Bengnér et al., 2021).