GLP1R and stroke disorder: GLP-1 RAs bind to GLP-1 receptors expressed in cardiomyocytes and vascular endothelial cells to cause beneficial effects on cardiovascular health, such as reductions in cardiovascular mortality (OR: 0.88; 95% CI: 0.80-0.96; p < 0.01; I2 = 14) and odds of stroke (OR: 0.84; 95% CI: 0.76-0.93; p < 0.01; I2 = 0%) in diabetic patients [33].