Woo et al. reported that compared to epidermal growth factor receptor (EGFR)-mutant and anaplastic lymphoma kinase (ALK)-rearranged adenocarcinomas, ROS1-rearranged adenocarcinomas were less likely to have distant metastases and more likely to have pericardial metastases and lymphangitis [10]. The gene discussed is ROS1; the disease is adenocarcinoma.