Woo et al. reported that compared to epidermal growth factor receptor (EGFR)-mutant and anaplastic lymphoma kinase (ALK)-rearranged adenocarcinomas, ROS1-rearranged adenocarcinomas were less likely to have distant metastases and more likely to have pericardial metastases and lymphangitis [10]. Here, ALK is linked to adenocarcinoma.