CD4 and malaria: In addition, females (AOR = 3.08, 95 % CI 1.37–6.93, p = 0.007) were three times more likely to be significantly associated with Plasmodium infection, the odds of malaria infection were 3 times higher in study participants with CD4+ T cell count <200 cells/μL as compared to those who have CD4+ T cell count >500 cells/μL (AOR = 3.09, 95 % CI 2.08–4.6, p < 0.001), and the odds of malaria was significantly two times higher in febrile children compared to afebrile children (AOR = 1.72, 95 % CI 1.01–2.11, p = 0.03).