Delgocitinib is a JAK1, JAK2, JAK3, and Tyk2 (pan-JAK) inhibitor, and 0.5% Delgocitinib Ointment is used to treat AD in adults and 0.25% Delgocitinib Ointment is used to treat AD in children (154). This evidence concerns the gene JAK1 and Alzheimer disease.