ATG16L1 and psoriasis: performed a study of 241 unaffected controls (mean age 35.01 ± 13.60 years, 131 females) without a personal or family history of psoriasis and 299 patients with psoriasis (mean age 41.11 ± 13.87 years, age of onset 20.90 ± 8.16 years, 132 females) through the genetic validation and found that mutations in the autophagy regulatory gene ATG16L1 were associated with psoriasis (85).