CD8A and Crohn disease: MTX-101 binding measured by gMFI on CD8 Tregs is driven by the number of CD8 receptors expressed on the cell surface (Figure 2E) due to the higher number of CD8 receptors on the cell surface relative to KIRs on cells both derived from healthy and disease donors (i.e., celiac disease and Crohn’s disease) (Figure 2E).