These hereditary predisposition syndromes for non-medullary thyroid cancer manifest with other types of lesions/tumors and include familial adenomatosis polyposis (FAP), PTEN-hamartoma tumor, Carney complex, Wermer syndrome (Multiple Endocrine Neoplasia Type 1 [MEN 1]), and DICER1 syndrome (20, 21). The gene discussed is PTEN; the disease is DICER1-related tumor predisposition.