Furthermore, in lymphoma samples from patients with gastric MALT lymphoma who received first-line HP eradication therapy (HPE), nuclear localization of CagA was significantly correlated with the presence of CagA signaling pathway-associated molecules, including phosphorylated-(p)-SHP-2, p-ERK, p-p38 MAPK, Bcl-2, and Bcl-xL in lymphoma cells [17]. The gene discussed is PTPN11; the disease is gastric mucosa-associated lymphoid tissue lymphoma.