We observed the presence of CagA in lymphoma cells in 54 (59%) of the 91 patients, and the presence of CagA was significantly correlated with HPE responsiveness (47/59 [80%] HPE-responsive cases vs. 7/32 [22%] HPE-irresponsive cases, p < 0.001; Table 1). The gene discussed is S100A8; the disease is lymphoma.