Finally, to explore the restoration of T cell functionality further, we assessed IL-2 production in splenocytes cultured with STmΔaroA or STmΔaroA/ΔansB-infected tumours, as well as primary colonic tumour fragments cultured in Matrigel, taken from mice that had received oral gavages of either strain of bacteria (as described in Fig. 2A). The gene discussed is IL2; the disease is colonic neoplasm.