PKM and neoplasm: Sub-analysis of metabolism-related DEGs revealed a striking suppression of multiple genes involved in glycolysis (Hk2, Pfkl, Pkm, Ldha, Eno1) by Salmonella-infected tumours at 16 h; this was paralleled by dampening of gene expression in the OXPHOS pathway (Cox5a, Atp5g1, mt-Nd1) at the same timepoint (Fig. 4D).