Interestingly, hepatic GNA12 expression levels, as determined via RNAseq, were positively correlated with HOMA-IR (homeostatic model assessment for insulin resistance; r = 0.41, p = 0.05) and negatively correlated with Si (insulin sensitivity index obtained from frequently-sampled intravenous glucose tolerance test [FS IVGTT]; r = −0.42, p = 0.05) (Supplementary Fig. 17). The gene discussed is GNA12; the disease is Insulin resistance.