To further comprehensively examine the effects of the CXCL10-CXCR3 axis and the production of IL4I1 on the treatment of lupus nephritis with hUC-MSCs, we used individual knockdown and double knockdown strategies for CXCR3 and IL4I1 (Supplementary Fig. 7d, e), and a strategy of in vivo neutralization with Anti-CXCL10 Ab for CXCL10 (Supplementary Fig. 7f). Here, CXCR3 is linked to lupus nephritis.