AGBL2 and Arthritis: As an expected finding corresponding to the overall cohort,8 several baseline characteristics were different in those already known to progress to arthritis compared with the non-yet-progressors, such as anti-CCP2 levels, co-occurrence of rheumatoid factor (RF) and double shared epitope alleles, where seven progressors (70%) and four (40%) non-progressors had double shared epitope alleles.