In contrast, Gjb2‐CKO/KO mice exhibit a large number of missing hair cells and neurons and rapidly progress to severe deafness, which does not mimic the clinical phenotype well.[117] Currently, only the GJB2 R75W mutation,[118] and the GJB2 35delG[51] mutant mouse model established by Li et al. The gene discussed is GJB2; the disease is deafness.