ABCC8 and Hyperglycemia: Owing to the young age at onset of the proband and her father and uncle, WES was conducted on the proband, resulting in the identification of the V357I mutation in ABCC8. Furthermore, this mutation was also found in her affected father and uncle, but not in her euglycemic mother, indicating that this mutation co-segregated with the hyperglycemia phenotype in this family.