TRIM21 and neoplasm: Furthermore, there was a rise in the quantity of Th2/GATA3 expression in the lung metastasis tissues of mice injected with the 4T1Cct6a group compared to 4T1EV, showing a decline in the tumours of the 4T1Cct6a+Trim21 mice group compared to the 4T1Cct6a+Trim21‐ΔRING mouse group (Figure S3A,C).