Studies have reported that age is an important predictor of glioma survival,35 and the prognosis of patients with high WHO grade gliomas is poor.36 Patients with gliomas, with 1p19q codeletion and IDH mutations, tend to have a relatively good prognosis.37,38 Similar to most biological targets of LGG, the expression level of DSN1 is closely related to the malignant features of tumors. Here, DSN1 is linked to central nervous system cancer.