WAC and osteoporosis: Yeon‐Suk Yang achieved bone‐targeted expression of the target gene and anti‐osteoporosis by transplanting bone‐targeting peptide motif (AspSerSer)6 onto AAV9‐VP2 capsid protein.[51] To further explore therapeutic interventions, we administered bone‐targeted rAAV9 vectors overexpressing WAC and PINK1 to SAMP6 and OVX mice.