Figure 7A presents a tree-map of keywords from the retrieved articles, where area of the rectangle corresponds to keyword frequency. Leading keywords were “breast cancer”, “immunotherapy”, and “tumor-infiltrating lymphocytes”, succeeded by “triple-negative breast cancer”, “prognosis”, “PD-L1”, “tumor microenvironment”, “neoadjuvant chemotherapy”, and “biomarkers”. Figure 7B shows the most frequently used keywords, as identified by co-occurrence analysis using VOSviewer. The gene discussed is CD274; the disease is breast carcinoma.