-4.2 grams of pectin reduced post-meal peak glucose (p < 0.01).-Acarbose (50 mg) and its combination with pectin increased plasma glucose 60–150 min post-meal (p < 0.01, p < 0.05, respectively).-The combination of acarbose and pectin reduced plasma insulin peaks (p < 0.05).-Hypoglycemia symptoms were common: eight out of nine patients were on placebo, two on 50 mg acarbose, two on 100 mg acarbose, five on pectin, and two on the combination.-All acarbose treatments increased breath hydrogen (p < 0.05). This evidence concerns the gene INS and Hypoglycemia.