Prognostic nutritional index (PNI) (calculated as serum albumin (g/dL) level × 10) + (lymphocyte (103/uL) × 0.005) is used to obtain prognostic information in patients with malignancy, heart failure, peripheral artery disease (PAD), stroke and coronary artery disease (10). The gene discussed is ALB; the disease is coronary artery disorder.