On the contrary, the subset of CD4+ T regulatory(Treg) lymphocytes is known to exert an immunosuppressive effect, mainly due tothe production of cytokines (IL-10 and TGFβ), and suppress the antitumorfunction of the effector cells of the tumor microenvironment, contributing thusto malignant growth and an unfavorable outcome [8]. The gene discussed is CD4; the disease is neoplasm.