Using RPA analysis, we categorized 362 HCC patients into three clusters with distinct prognoses: C1 (AJCC T1-3 with KIF20A of 0.05-4.46), C2 (AJCC T3-4 with KIF20A of 0.05-4.46 and T1-2 with KIF20A of 4.47-21.25), and C3 (AJCC T3-4 with KIF20A of 4.47-21.25; P<0.05, Figures 8B, C). Here, KIF20A is linked to hepatocellular carcinoma.