CRP analysis in the context of colorectal cancer (CRC) has shown worse overall and cancer-free survival, with a low leukocyte-to-CRP ratio (LCR) and low CRP-albumin ratio, suggesting a definitive predictive relevance for stage II/III CRC and labeling LCR as the most sensitive biomarker for cancer progression55. The gene discussed is CRP; the disease is colorectal carcinoma.