Higher CRP levels accelerate atherosclerosis's primary development and progression14. CRP-induced activation of the immune system increases lipid accumulation and thus plaque formation15.CRP’s interaction with the endothelium mitigates nitric oxide formation causing plaque sensitivity with consequent vasoconstrictive effects resulting in an increased infarct size in myocardial infarction (MI)14,16. This evidence concerns the gene CRP and atherosclerosis.