CRP has also been used as a diagnostic marker of acute appendicitis61.The use of CRP in diagnosing acute neonatal sepsis has shown results with a sensitivity of 76.92%62, whereas in adults, CRP was able to diagnose and differentiate between sepsis with and without bacteremia, especially when used in conjunction with procalcitonin63. The gene discussed is CRP; the disease is bacterial infectious disease with sepsis.