Genotyping and follow-up association analysis showed strong association of rs1781133/ANKRD65 (OR =2.10, 95%Cl = 1.06–3.08, P = 0.003), rs2274791/TTLL10 (OR = 1.97, 95%Cl = 1.36-2.62, P = 0.025), rs71628928/RNF223 (OR = 1.82, 95%Cl = 0.97-1.92, P = 0.041), and rs609805/SCNN1D (OR = 2.21, 95%Cl = 1.92-3.09, P = 0.001) with T2DM in the study population (Table-V). The gene discussed is SCNN1D; the disease is type 2 diabetes mellitus.