In another study, clinician consultation is recommended in which population screening in asymptomatic men is not recommended.11 While no difference was found in prostate cancer mortality over 10 years between non-screening standard practice and PSA screening, it was reported that screening reduced the number of low-risk prostate cancer cases.12 A population-based prostate cancer screening is not recommended in most countries. The gene discussed is KLK3; the disease is prostate carcinoma.