When patients with gastric cancer undergo chemotherapy, the body may enter a state of stress and cause immune function suppression.18 It was shown in this study that the levels of IgA, IgM and IgG of the two groups after treatment were lower than those before treatment, and those in the probiotics combined with enteral nutrition group were lower than those in the enteral nutrition group. The gene discussed is CD40LG; the disease is gastric cancer.