GFAPλ like GFAPδ contains exon 7a but keeps exons 8 and 9 transcriptions, while GFAPμ only contains exons 1 and 3 with a premature termination codon following exon 3.63,64 Moreover, GFAP has four alternative isoforms collectively termed GFAP + 1 present in astrocyte subgroups associated with single nucleotide frame-shift variants: GFAPΔEx6, GFAPΔ164, GFAPΔ135 and GFAPΔEx7.65 Increased levels of specific GFAP isoforms have been reported over the course of amyloid pathology. This evidence concerns the gene GFAP and amyloidosis.