Diosmin, through a ROS‐mediated mechanism, overexpression of caspase 9 and 3, p53 genes, and downregulation of Bcl‐2 and matrix metalloproteinases‐2 and 9 genes caused apoptosis in skin cancer cells (A431) (Buddhan & Manoharan, 2017). The gene discussed is CASP9; the disease is skin neoplasm.