Diosmin showed anticancer activity in hepatocarcinoma, breast, and colorectal cancer cells with the activation of Fas and Bax apoptotic factors, which cause the apoptosis of the cell also through cyt C (cytochrome C) releasing from mitochondria, inhibiting the translocation of NF‐кB, activating different caspases, and triggering the cell cycle in the G2/M phase (Koosha et al., 2019). Here, FAS is linked to colorectal cancer.