SERF2 and breast cancer: This concentration of SERF2 is below the concentration present in different human cells such as 48 ppm (~ 7 μM) in U2OS cells and 163 ppm (~ 23 μM) in MCF7 breast cancer cells in the crowded in vivo environment.70 All rG4 forming sequences do not form droplets (Supplementary Data Fig. 5e) on their own in crowding conditions.