This concentration of SERF2 is below the concentration present in different human cells such as 48 ppm (~ 7 μM) in U2OS cells and 163 ppm (~ 23 μM) in MCF7 breast cancer cells in the crowded in vivo environment.70 All rG4 forming sequences do not form droplets (Supplementary Data Fig. 5e) on their own in crowding conditions. Here, SERF2 is linked to breast carcinoma.