FLI1 and leukemia: DMRs were highly patient-specific, with only 89 genes containing DMRs in all three patients; however, this set included genes involved in leukemia, hematopoiesis, and multipotency, such as FLI1, EGFL7, and TCF15 (Table S7).36–40 We then analyzed the genomic features associated with DMRs across our cohort (Figure 4E, S6A).