AKT1 and glioblastoma: Bioinformatic analysis suggested that elevated HULC levels in their GBM tissues correlated with poorer prognosis and the HULC overexpression stimulated the migration, invasion, and proliferation of human GBM U87 cells by surging the HIF-related EGFR/PI3K/AKT signaling pathway [[65], [66], [67], [68], [69]].