Analysis of expression of immune-related genes in GBM, IDH-WT revealed significantly lower expression of PD-L2 (PDCD1LG2) in CR-mut compared to CR-WT (q < .05), which was lower in all 3 CR gene groups but only significantly in HM-mut GBM, IDH-WT (P < .05; Figure 3C). The gene discussed is IDH1; the disease is glioblastoma.