IDH1 and astrocytoma (excluding glioblastoma): Molecular profiling of a large cohort of HGGs including grade 4 GBM, IDH-WT, and grade 3/4 astrocytoma, IDH-mut have enabled the exploration of potential associations of CR genes with biomarkers of clinical significance in these malignant astrocytic tumors, yielding some significant observations among subgroups of interest.