A similar pattern of staining intensity was detected in OLP lesions in which maximum staining intensity (grade III) showed up in the total number of lesions (18/18), i.e., 100%, whereas in OSCC lesions the expression of DAPK-1 was mostly mild (grade I) at 54.54% (12/22) of the lesions, moderate (grade II) in 36.36% (8/22) of OSCCs, and only 16.66% (2/22) of the samples were characterized by an intense expression (grade III). The gene discussed is DAPK1; the disease is oral lichen planus.