ICI-HP, immune checkpoint inhibitor-induced hypopituitarism; IHP, idiopathic hypopituitarism; IAD, isolated adrenocorticotropic hormone deficiency; ITD, isolated thyroid-stimulating hormone deficiency; ACTH, adrenocorticotropic hormone; TSH, thyroid-stimulating hormone. This evidence concerns the gene POMC and central congenital hypothyroidism.