NUP98 and leukemia: Additionally, they showed that the structural characteristics directing the condensation are embedded within the N-terminus of NUP98 and possess the ability to trigger leukemia-specific gene expression when incorporated into oncogenic fusion proteins (Table 4).290 These observations were confirmed by a subsequent study showing that NUP98 fusion oncoproteins contain an LCR that is prone to LLPS, driving the transformation of hematopoietic cells.291