We also constructed deletion mutants of the coiled-coil domain (TSG101 dCC), which was reported as the interaction domain with DAXX [24], and TSG101 d901bp (delta154-1054), which consists of only 28 amino acids’ peptides missing residues 204-1104 and is predominant in most cancer tissues [38] (Fig. 3A and B). This evidence concerns the gene TSG101 and cancer.