In more detail, SD rats accounted for 53.2% (193/363), Wistar rats accounted for 4.4% (16/363), C57/BL6J mice accounted for 18.7% (68/363), FVB mice accounted for 9.9% (36/363), Spontaneous T2DM C57BLKS/J db/db mice accounted for 8.3% (30/363), and the Generation of the Cardiac-Specific SIRT1 Knockout (SIRT1 KO) mice accounted for 5.5% (20/363). This evidence concerns the gene SIRT1 and type 2 diabetes mellitus.