Genes for chemokine receptors Ccr7, Cxcr3 and Cxcr6, which interact with the respective T cell-attracting chemokines CCL19, CXCL9 and CXCL16, were highly expressed in CD8+T cells within intracranial tumors, with comparable expression levels in PC treated and control mice (figure 5E). This evidence concerns the gene CXCL16 and pachyonychia congenita.