CD8A and infection: To assess the ability of CD8+ T cells to induce neuronal death, we used an in vitro coculture system in which CD8+ T cells were isolated from the spleens of adult animals at 7 DPI MHV‐A59 infection, then cocultured with primary cortical neurons that had been inoculated with MHV at MOI 0.5 or media alone 24 h prior.