CRP and Hepatic fibrosis: Although ACBP/DBI plasma concentrations increase with age and BMI, which both are risk factors for MASLD [21, 35], it appears that ACBP/DBI levels are particular high in patients with histologically diagnosed MASLD or liver fibrosis, correlating with various laboratory parameters of liver inflammation (CRP), insufficiency (high bilirubin and INR, low albumin) and damage (AST, alkaline phosphatase).