CRP and hepatitis A virus infection: ACBP/DBI plasma levels also correlated with individual laboratory parameters indicating inflammation (C-reactive protein), hepatocyte damage (AST), three signs of liver dysfunction (high bilirubin; high international normalized ratio [INR], which is elevated when blood clotting is slowed; low albumin), as well as with serum alkaline phosphatase (which increases in hepatitis and cirrhosis) [34].