SLE-related multicellular pathway modules consist of “Interferon alpha/beta signaling” (type 1 interferon) in all cell types, “Type II interferon signaling (interferon-gamma)” in nCM and classical dendritic cell (cDC), “Cross-presentation of particulate exogenous antigens (phagosomes)” in cM and “Granzyme A-mediated apoptosis pathway” in T8, etc. (Fig. 6a, Supplementary Data 3). This evidence concerns the gene IFNG and systemic lupus erythematosus.