By analysing protein scores and coverage (Fig. 3 D, E) and retrieving whether these proteins were reported to regulate the Wnt signalling pathway, we identified that the top-ranked protein overall, actin gamma 1 (ACTG1), despite its capacity to bind to FATS (Fig. S1B) and having been previously reported to be Given its involvement in a wide range of cancers, it was not possible to ascertain whether this protein could affect the Wnt/β-catenin signaling pathway in breast cancer cells (Fig. S1C, D). This evidence concerns the gene C10orf90 and cancer.