Analysis of cytoskeleton-associated genes including RHOA, MYO9A, MYO9B, PXN, VCL, VASP, ACTβ, MYH9, as well as a selection of proto-oncogenic and tumour-suppressive targets related to drug anti-metastasis, such as BRAF, CDK4, EGFR, KEAP1, KRAS, PIK3CA, PTEN, PTPRD, TP5380–84 revealed no significant changes in expression levels, except for PXN, VASP, and KEAP1 (Fig. 7H–K). Here, CDK4 is linked to neoplasm.