AOX1 and infection: The non-linearity is thought to be explained by the concentration-dependent aldehyde oxidase inhibition reproducible in non-human primates,74 and any additional infection-specific contribution remains unclear as of now. Pharmacokinetic studies of parenteral (including intravenous75) administration in NiV-B-inoculated non-human primates would be the next key step in favipiravir evaluation.